At the 85th Scientific Sessions of the American Diabetes Association, L-Nutra Health, the medical branch of nutrition technology company L-Nutra, highlighted the effectiveness of lifestyle medicine in reversing the progression of type 2 diabetes with compelling real-world evidence. The data shows the results of a complete, scientifically supervised diet and lifestyle program that addresses insulin resistance, visceral obesity, and cellular aging in order to assist the treatment and possible reversal of type 2 diabetes and metabolic illness at their core.
Results from 125 participants in L-Nutra Health’s diabetic Remission and Regression Program (DRRP) showed significant weight loss, decreases in the usage of diabetic medications, and improvements in glycemic control—all without the need for medication or lifestyle changes.
“This is a powerful demonstration of what happens when you replace reactive care with proactive, personalized nutrition therapy,” stated Dr. Joseph Antoun, MD, CEO and Chairman of L-Nutra. “Instead of managing symptoms, we’re helping patients resolve the underlying dysfunction driving their disease.”
Key outcomes presented:
- The mean age of the study volunteers was 61.7 years, with body mass index of 31.8, diabetes duration of 10.7 years and baseline HbA1c of 7.6%.
- 54% of participants reduced diabetes medications at 3 months; 68% at 6 months
- HbA1c decreased by 0.5 % at 3 months and maintained at 6 months
- Average weight loss of 4.0 kg at 3 months and 5.1 kg at 6 months
- Diabetes Treatment Satisfaction Score (DTSQ) improved from 26.9 at baseline to 30.4 at 6 months
The abstract was presented by Ashley Bizzell RD, LDN, CDCES, Director of Clinical Nutrition and Global Training at L-Nutra Health, who leads the clinical nutrition team delivering the intervention.
“These findings are truly encouraging—pairing the fasting-mimicking diet with personalized guidance and support from a dietitian presents a compelling approach to driving remission in type 2 diabetes,” stated Bizzell. “As a dietitian, it reinforces the critical role that nutrition-centered care can play in reversing chronic disease and restoring metabolic health.”
“The Fasting Mimicking Diet (FMD) is a patented, nutrition-based therapeutic that delivers the cellular and metabolic benefits of fasting—without full food deprivation,” stated Dr. William Hsu, MD, Chief Medical Officer of L-Nutra and former VP at Harvard’s Joslin Diabetes Center. “When integrated with physician oversight and registered dietitian support, it enables clinically significant metabolic improvements with less dependence on costly medications and minimal lifestyle disruption—an outcome rarely achieved in standard care.”
An Innovative Model Based on Personalized, Root-Cause Care
The L-Nutra Health program integrates evidence-based nutrition protocols—including a patented, low-glycemic dietary intervention that mimics the effects of fasting—with bi-monthly Registered Dietitian coaching, medical oversight by a team of board-certified lifestyle medicine physicians, laboratory review, and medication reduction as appropriate. Patients receive individualized care plans that aim to drive disease remission and regression, optimize weight care, improve insulin sensitivity and biological age score —shifting the treatment paradigm from glucose control to true metabolic restoration.
Backed by over 25 years of research, including funding from the NIH and clinical partnerships with 34 global institutions, this model offers a cost-effective, sustainable, and scalable alternative to pharmaceutical-first diabetes care.
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